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所在位置:所有产品 > 抗体抗原 > 一抗 > MMP8抗体
MMP8抗体图片
产品货号:
Z34634
中文名称:
MMP8抗体
英文名称:
Anti-MMP8 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-MMP8 Antibody
指标别名CLG1;HNC;Matrix metalloproteinase 8;MMP 8;MMP8;Neutrophil collagenase;PMNL CL;PMNL collagenase
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB,IHC,ICC/IF
基因名称MMP8
抗体来源Rabbit
抗体类型IgG
免疫原A synthesized peptide derived from human MMP8
实际分子量53KD
成分500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
纯化方式Affinity-chromatography
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料MMP8 (Matrix metalloproteinase 8) is a member of the family of matrix metalloproteinases.It is distinct from the collagenase of skin fibroblasts and synovial cells in substrate specificity and immunologic crossreactivity.MMP8 is mapped to 11q21-q22.MMP8 is an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes,is expressed by leukocytes and chorionic cytotrophoblast cells.The enzyme exhibits 58% homology to human fibroblast collagenase and has the same domain structure.It consists of a 20-residue signal peptide,and an 80-residue propeptide that is lost on autolytic activation by cleavage of an M-L bond.MMP8 was found to possess 57% identity with the deduced protein sequence for fibroblast collagenase with 72% chemical similarity.Matrix metalloproteinases (MMPs) have fundamental roles in tumor progression,but most clinical trials with MMP inhibitors have not shown improvements in individuals with cancer.MMP8 has a paradoxical protective role in cancer and provides a genetic model to evaluate the molecular basis of gender differences in cancer susceptibility.
Uniprot IDP22894
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称Neutrophil collagenase
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:20~100ICC/IF
Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100

相关搜索:MMP8抗体MMP8单抗Anti-MMP8 Antibody
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